
Rae,
I changed to twist shifters many years ago because the standard shimano shifters made my hands ache, especially my thumbs. My mother has some kind of arthritis (can never remember which but both hips replaced!)so I'm expecting to get it later in life.
I have no problem with twist shifters although some people seem snobby about them. No idea why !! They are cheap to buy on chain reaction.
I have taken cod liver oil and glucosamine sulphate for a few years now, because of my family history. It may be in the mind but I say it definately works.